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mntA [2017-10-19 17:43:35]
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mntA [2017-10-19 17:43:35]

manganese [category|search|ABC transporter] (binding protein, lipoprotein)
Locus
BSU30770
Isoelectric point
6.16
Molecular weight
33.26 kDa
Protein length
306 aa Sequence Blast
Gene length
918 bp Sequence Blast
Function
manganese uptake
Product
manganese [category|search|ABC transporter] (binding protein)
Essential
no
Synonyms
ytgA

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
3,145,038 → 3,145,958

Phenotypes of a mutant

  • essential according to Kobayashi et al., but a mutant has been constructed and studied by Que and Helmann, 2000
  • The protein

    Protein family

  • bacterial solute-binding protein 9 family (according to Swiss-Prot)
  • Paralogous protein(s)

    Structure

  • 1TOA (zinc-binding protein from Treponema pallidum, 46% identity)
  • Localization

  • cell membrane (according to Swiss-Prot), extracellular lipoprotein (signal peptide) PubMed
  • Expression and Regulation

    Operons

    Description

    Regulatory mechanism

  • MntR: repression, PubMed, in MntR regulon
  • Regulation

  • repressed at high Mn(II) concentrations (MntR) PubMed
  • Additional information

  • A ncRNA is predicted between 'mntA' and 'menC' PubMed
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    Biological materials

    Mutant

  • MGNA-A285 (ytgA::erm), available at the NBRP B. subtilis, Japan
  • BKE30770 (ΔmntA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATTTCTCCTCCTCTTTG, downstream forward: _UP4_TAAAGAAAAGAGGTGGAGGA
  • BKK30770 (ΔmntA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATTTCTCCTCCTCTTTG, downstream forward: _UP4_TAAAGAAAAGAGGTGGAGGA
  • Labs working on this gene/protein

  • John Helmann, Cornell University, USA Homepage
  • References

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